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DISCLAIMER:
The statements contained herein have not been evaluated by the Food And Drug Administration. It is not intended to diagnose, treat, cure or prevent disease. The statements are for informational purposes only and is it not meant to replace the services or recommendations of a physician or qualified health care practitioner. Those with health problems or pregnancy are specifically advised that they should consult their physician before taking colostrum or any nutritional supplement.



M. Borissenko
May, 2002

TRANSFER FACTOR


INTRODUCTION

The principle action of Transfer factor is thought to be based on the premise that key immune information can be transferred from one cell or organism to another. These donor cells thus convey certain information to the recipient cell's immune system thereby bolstering its ability to fight disease and infection. Transfer factor molecules are thought to be involved in one of the key elements in the immune response - accumulative memory of past pathogen exposure. These very small molecules produced by the immune system's T cells thus are thought to function in allowing the immune system to remember conditions to which immunity has already been established in the past - thus elevating the body's own immune system to specific pathogens. This is especially exciting when you consider that it may be possible to transfer this memory from one individual to another, or even further from one species to another.

One of the main functions of the immune system is to recognize pathogens and then to fight, neutralize, and destroy them. The sooner the immune system can complete this action the more likely it is able to effectively defend the body from further infection. When a person is exposed to a disease such as chickenpox the immune system develops not only antibodies to act against the disease but also memory of the disease. It is this memory that prevents the same person being re-infected later in life. In this way the individual has developed immunity against the disease and this is why we only get chickenpox once.

It has been theorized that there are several million naturally occurring Transfer factors circulating in the human body. In the first instance a great number of these Transfer factors are first introduced from the mother to her offspring during the process of passive transfer of immunity or passive immunity. Whether in humans this occurs prior to birth, in utero, has yet to be established. However, it is believed that this phenomenon does occur after birth in the form of colostrum and possibly milk. Colostrum is thought to be the greatest single source of Transfer factor. Bovine colostrum is an ideal source of Transfer factor as it is available in significant quantities. In addition Transfer factor is not species specific and humans and other animals can benefit from cows colostrum.

Transfer factor actions to elevate the recipient's immune response to specific pathogens. Though by no means conclusive the results of preliminary clinical studies have shown that Transfer factor may potentially be effective against the following diseases and disorders: Cancer, HIV/AIDS, Autoimmune Disease, Influenza, Multiple Sclerosis, Alzheimer's, Parkinson's, Arthritis, Lupus Erythematosis, Protozoa infection, and the common cold.

At present there are several companies marketing Transfer Factor, on it's own - with the colostrum portion removed. They manufacture this material by dialyzing bovine colostrum - similar to making sausage. The very small molecules, like water pass through the dialysis membrane (sausage casing) while the large molecules (meat) are retained inside. The material that passes through has been termed Transfer Factor. The unfortunate thing about these products is that they have left the most important thing out - that is all the other natural constituents of colostrum. For example Transfer Factor does not contain any immune factors nor growth factors nor antibodies. These are all important in not only fighting disease but maintaining overall good health as well.

One important thing to remember is that all the constituents in colostrum work together - this includes Transfer Factor. All these things work together in a synergistic manner (help one another) and in this way the overall effect of colostrum is greater then the sum of the individual components. The "Battle of Good Health" is fought by an army and this includes soldiers, rifles, ammunition, tanks, cannons, airplanes, bombs, ships, and all the various elements which compose an army. To win the war you need all these various components working together. Transfer Factor's role in the battle is probably best described as that of the spies and counter-intellegence. Now no matter how good the intelligence information is - you can't win a war with that alone.

 

 


TRANSFER FACTOR FREFERENCES

White, R.I., Schork, M>A>, Sloan, H., Orringer, M.B., Kirsh, M.M. Adjuvant Treatment Using Transfer Factor for Bronchogenic Carcinoma: Long-Term Follow-Up. (1992) Ann Thorac Surg March 53: 391-6

Fudenburg, H.H., Pizza, G. Transfer Factor 1993 New Frontiers Progress In Drug Research, 42 (1994) 309-400.

Kirkpatrick, C.H. Properties and Activities of Transfer Factor. (1975) J Allergy Clin Immunol, June 55: 411-21.

Kirkpatrick, C.H. Activities and Characteristics of Transfer Factors. (1996) Biotherapy 9: 13-6.

Carey, J.T., Lederman, M.M., Toosi, Z., Edmonds, K., Hodder, S., Calabrese, L.H., Profitt, M.R., Johnson, C. Augmentation of Skin Test Reactivity and Lymphocyte Blastogenesis in Patients With AIDS Treated With Transfer Factor. (1987) JAMA Feb 257: 651-5.

Dwyer, J.M. Transfer Factor in the Age of Molecular Biology:a Review. (1996) Biotherapy, 9:7clerosing Panencephalitis. (1975) Dec 211:39-40

Louie, E., Borkowsky, W., Klesius, P.H., Haynes, T.B., Gordon, S., Bonk, S., Lawrence, H.S. Treatment of Cryptosporidiosis With Oral Bovine Transfer Factor. (1987) Clin Immunol Immunopath. Sep 44: 329-34.

Spitler, L.E., Miller, L. Clinical Trials of Transfer Factor in Malignancy. 3: 549-64.

Steele, R.W., Myers, M.G., Vincent, M.M. Transfer Factor for the Prevention of Varicella-Zoster Infection in Childhood Leukemia. (1980) N Engl J Med Aug 303: 355-9.

Spitler, L.E. Transfer Factor in Immunodeficiency Diseases. (1979) Ann NY Acad Sci 332: 228-35.


ã Copyright Institute of Colostrum Research 2002

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