Suckling Induces Rapid Intestinal Growth and Changes in Brush Border Digestive Functions of Newborn Pigs.

Manuscript received 10 June 1996. Initial reviews completed 30 July 1996. Revision accepted 22 November 1996. Hongzheng Zhang, Christiane Malo*, and Randal K. Buddington

Department of Biological Sciences, Mississippi State University, Mississippi State, MS 39762-5759 and * Membrane Transport Research Group, Department of Physiology, B.P. 6128, Succursale Centre-ville, Université de Montréal, Montréal, Québec, Canada H3C3J7

The interplay between suckling, intestinal growth and brush-border membrane functions is critical during the perinatal period. The present study investigates changes in intestinal dimensions, activities of four brush border membrane hydrolases (lactase, sucrase, maltase and aminooligopeptidase) and rates of sugar and amino acid uptake by intact tissues and brush border membrane vesicles during the first 24 h of suckling. Total intestinal weight, mucosal weight and protein content increased 58%, 80% and 126% (P

American Journal of Clinical Nutrition, Vol 34, 252-257, Copyright © 1981 by The American Society for Clinical Nutrition, Inc

Word Count: 139 Words